2010 Geno/Grinder - Review of a High Throughput Sample Homogenizer
291 Route 22 East
Lebanon, NJ 08833
TEL: (908) 253-3444
FAX: (908) 575-1660
In our labs we have used the GenoGrinder for smashing seeds for GMO analysis, cracking yeast and fungi, and for the disruption of biofilms cultured in 96-well plates. This mill allows for high throughput as compared to the manual alternative. We actively use and support this product.
The 2010 GenoGrinder is an updated model of the original GenoGrinder 2000 laboratory mill. It is specifically designed for vigorous vertical shaking of deep-well plates. It was originally designed to prepare plant tissue for extractions of nucleic acid, protein, and other constituents by shaking the tissue, steel balls and a buffering agent together in each well of a titer plate. The application of this tool can be expanded to include microorganisms when small silica beads are used instead of steal grinding balls. Microbes can be disrupted in standard 96-well plates as opposed to deep well plates.
Sample material that can be prepared includes bacteria, yeasts, molds, seeds, stems, roots, leaves, and certain animal tissue. Because the unique vertical shaking motion of the GenoGrinder is so strong, many seeds and other forms of plant tissue can also be pulverized dry in plates with the help of one or two grinding balls per well.
While the GenoGrinder clamp is designed to hold two standard deep-well titer plates, it can adapt to anything of the same general dimensions (5 in. long x 3 in. wide x 2 in. high). This includes any standard microwell plate, racks which hold multiple individual vials, and other possible configurations. The GenoGrinder is supplied with height adjustment spacers of different thickness to accommodate different sample holders with heights up to 2 1/4 inches.
In addition to microwell plates, 24 Well Vial Set are available for the dry grinding of seeds (e.g., corn and soy). This Vial Set System includes racked vials, a 24 pin magnet, and magnet stand/separator. This system allows for the high throughput homogenization of seeds.
A digital timer displays both the full timer setting along with the minutes and seconds remaining in the grinding cycle. An adjustable dial allows the operator to set the precise stroke rate between 500 and 1750 strokes per minute.
The GenoGrinder cabinet has two safety interlocks, a lockdown latch, and a pneumatic cylinder to stabilize the lid movement. The clamping mechanism latches have secondary locking tabs for additional safety.
Vial Sets for High Throughput Sample
Grinding and Homogenization